Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis

Ewing sarcoma (EWS) is the second most common bone and soft tissue-associated malignancy in children and young adults. It is driven by the fusion oncogene EWS/FLI1 and characterized by rapid growth and early metastasis. We have previously discovered that the mRNA binding protein IGF2BP3 constitutes...

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Vydáno v:Front Oncol
Hlavní autoři: Mancarella, Caterina, Caldoni, Giulia, Ribolsi, Irene, Parra, Alessandro, Manara, Maria Cristina, Mercurio, Arthur M., Morrione, Andrea, Scotlandi, Katia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347992/
https://ncbi.nlm.nih.gov/pubmed/32719743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00994
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