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Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries
Schwann cell grafts support axonal growth following spinal cord injury, but a boundary forms between the implanted cells and host astrocytes. Axons are reluctant to exit the graft tissue in large part due to the surrounding inhibitory environment containing chondroitin sulphate proteoglycans (CSPGs)...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347606/ https://ncbi.nlm.nih.gov/pubmed/32647242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67526-0 |
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