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Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries

Schwann cell grafts support axonal growth following spinal cord injury, but a boundary forms between the implanted cells and host astrocytes. Axons are reluctant to exit the graft tissue in large part due to the surrounding inhibitory environment containing chondroitin sulphate proteoglycans (CSPGs)...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Warren, Philippa M., Andrews, Melissa R., Smith, Marc, Bartus, Katalin, Bradbury, Elizabeth J., Verhaagen, Joost, Fawcett, James W., Kwok, Jessica C. F.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347606/
https://ncbi.nlm.nih.gov/pubmed/32647242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67526-0
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