Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries

Schwann cell grafts support axonal growth following spinal cord injury, but a boundary forms between the implanted cells and host astrocytes. Axons are reluctant to exit the graft tissue in large part due to the surrounding inhibitory environment containing chondroitin sulphate proteoglycans (CSPGs)...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Warren, Philippa M., Andrews, Melissa R., Smith, Marc, Bartus, Katalin, Bradbury, Elizabeth J., Verhaagen, Joost, Fawcett, James W., Kwok, Jessica C. F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347606/
https://ncbi.nlm.nih.gov/pubmed/32647242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67526-0
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