Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice

Chondroitin sulphate proteoglycans (CSPGs) are extracellular matrix molecules whose inhibitory activity is attenuated by the enzyme chondroitinase ABC (ChABC). Here we assess whether CSPG degradation can promote compensatory sprouting of the intact corticospinal tract (CST) following unilateral inju...

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Publicado en:Eur J Neurosci
Autores principales: Starkey, Michelle L., Bartus, Katalin, Barritt, Andrew W., Bradbury, Elizabeth J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851235/
https://ncbi.nlm.nih.gov/pubmed/23061434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12017
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