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Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice

Chondroitin sulphate proteoglycans (CSPGs) are extracellular matrix molecules whose inhibitory activity is attenuated by the enzyme chondroitinase ABC (ChABC). Here we assess whether CSPG degradation can promote compensatory sprouting of the intact corticospinal tract (CST) following unilateral inju...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Starkey, Michelle L., Bartus, Katalin, Barritt, Andrew W., Bradbury, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851235/
https://ncbi.nlm.nih.gov/pubmed/23061434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12017
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