Chondroitinase ABC Promotes Sprouting of Intact and Injured Spinal Systems after Spinal Cord Injury

Chondroitin sulfate proteoglycans (CSPGs) are inhibitory extracellular matrix molecules that are upregulated after CNS injury. Degradation of CSPGs using the enzyme chondroitinase ABC (ChABC) can promote functional recovery after spinal cord injury. However, the mechanisms underlying this recovery a...

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Главные авторы: Barritt, A. W., Davies, M., Marchand, F., Hartley, R., Grist, J., Yip, P., McMahon, S. B., Bradbury, E. J.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2006
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339436/
https://ncbi.nlm.nih.gov/pubmed/17050723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2980-06.2006
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