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Substrate Specificity and Biochemical Characteristics of an Engineered Mammalian Chondroitinase ABC

[Image: see text] Chondroitin sulfate proteoglycans inhibit regeneration, neuroprotection, and plasticity following spinal cord injury. The development of a second-generation chondroitinase ABC enzyme, capable of being secreted from mammalian cells (mChABC), has facilitated the functional recovery o...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Warren, Philippa M., Fawcett, James W., Kwok, Jessica C. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153898/
https://ncbi.nlm.nih.gov/pubmed/34056277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c06262
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