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Immature astrocytes promote CNS axonal regeneration when combined with chondroitinase ABC

Regeneration of injured adult CNS axons is inhibited by formation of a glial scar. Immature astrocytes are able to support robust neurite outgrowth and reduce scarring, therefore, we tested whether these cells would have this effect if transplanted into brain injuries. Utilizing an in vitro spot gra...

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Autors principals: Filous, Angela R., Miller, Jared H., Coulson-Thomas, Yvette M., Horn, Kevin P., Alilain, Warren J., Silver, Jerry
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940988/
https://ncbi.nlm.nih.gov/pubmed/20629049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20820
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