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Immature astrocytes promote CNS axonal regeneration when combined with chondroitinase ABC

Regeneration of injured adult CNS axons is inhibited by formation of a glial scar. Immature astrocytes are able to support robust neurite outgrowth and reduce scarring, therefore, we tested whether these cells would have this effect if transplanted into brain injuries. Utilizing an in vitro spot gra...

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Detalhes bibliográficos
Main Authors: Filous, Angela R., Miller, Jared H., Coulson-Thomas, Yvette M., Horn, Kevin P., Alilain, Warren J., Silver, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940988/
https://ncbi.nlm.nih.gov/pubmed/20629049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20820
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