Increased Chondroitin Sulfate Proteoglycan Expression in Denervated Brainstem Targets Following Spinal Cord Injury Creates a Barrier to Axonal Regeneration Overcome by Chondroitinase ABC and Neurotrophin-3

Increased chondroitin sulfate proteoglycan (CSPG) expression in the vicinity of a spinal cord injury (SCI) is a primary participant in axonal regeneration failure. However, the presence of similar increases of CSPG expression in denervated synaptic targets well away from the primary lesion and the s...

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Main Authors: Massey, James M., Amps, Jeremy, Viapiano, Mariano S., Matthews, Russell. T., Wagoner, Michelle R., Whitaker, Christopher M., Alilain, Warren, Yonkof, Alicia L., Khalyfa, Abdelnaby, Cooper, Nigel G. F., Silver, Jerry, Onifer, Stephen M.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270474/
https://ncbi.nlm.nih.gov/pubmed/17540369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.03.029
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