Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement

Orthodontic force-induced osteogenic differentiation and bone formation at tension side play a pivotal role in orthodontic tooth movement (OTM). Platelet-derived growth factor-BB (PDGF-BB) is a clinically proven growth factor during bone regeneration process with unclear mechanisms. Fibroblasts in p...

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Publicat a:Sci Rep
Autors principals: Jin, Yuqin, Ding, Liang, Ding, Zhuang, Fu, Yong, Song, Yuxian, Jing, Yue, Li, Qiang, Zhang, Jianyun, Ni, Yanhong, Hu, Qingang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347599/
https://ncbi.nlm.nih.gov/pubmed/32647179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68068-1
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