A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signals

Growth factor-binding domains identified in various extracellular matrix (ECM) proteins have been shown to regulate growth factor activity in many ways. Recently we identified a fibronectin peptide (P12) that can bind platelet-derived growth factor BB (PDGF-BB) and promote adult human dermal fibrobl...

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Main Authors: Zhu, Jia, Lin, Fubao, Brown, Deborah A., Clark, Richard A.F.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961502/
https://ncbi.nlm.nih.gov/pubmed/24304816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.463
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