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Programmable One-pot Synthesis of Heparin Pentasaccharide Fondaparinux

The clinically approved Fondaparinux (Arixtra) has been used for the treatment of deep vein thrombosis (DVT) and acute pulmonary embolism (PE) since 2002, and considered to be better than the low molecular-weight heparin (LMWH) in terms of anticoagulation response, duration of action and biosafety....

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Bibliographic Details
Published in:Org Lett
Main Authors: Dey, Supriya, Lo, Hong-Jay, Wong, Chi-Huey
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347301/
https://ncbi.nlm.nih.gov/pubmed/32496799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01386
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