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Preactivation-Based, One-Pot Combinatorial Synthesis of Heparin-like Hexasaccharides for the Analysis of Heparin–Protein Interactions

Heparin (HP) and heparan sulfate (HS) play important roles in many biological events. Increasing evidence has shown that the biological functions of HP and HS can be critically dependent upon their precise structures, including the position of the iduronic acids and sulfation patterns. However, unra...

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Detalhes bibliográficos
Main Authors: Wang, Zhen, Xu, Yongmei, Yang, Bo, Tiruchinapally, Gopinath, Sun, Bin, Liu, Renpeng, Dulaney, Steven, Liu, Jian, Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094016/
https://ncbi.nlm.nih.gov/pubmed/20623566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201000987
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