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Combinatorial one-pot chemoenzymatic synthesis of heparin

Contamination in heparin batches during early 2008 has resulted in a significant effort to develop a safer bioengineered heparin using bacterial capsular polysaccharide heparosan and recombinant enzymes derived from the heparin/heparan sulfate biosynthetic pathway. This requires controlled chemical...

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Detalhes bibliográficos
Publicado no:Carbohydr Polym
Main Authors: Bhaskar, Ujjwal, Li, Guoyun, Fu, Li, Onishi, Akihiro, Suflita, Matt, Dordick, Jonathan S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379424/
https://ncbi.nlm.nih.gov/pubmed/25817684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carbpol.2014.10.054
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