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Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives

Heparin (H) and heparan sulfate (HS) belong to the glycosaminoglycan (GAG) family of oligosaccharides, and their sequences and sulfation patterns are known to regulate the functions of various proteins in biological processes. Among these, the 6-O-sulfation of HS/H contributes most significantly to...

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Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Dey, Supriya, Wong, Chi-Huey
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115620/
https://ncbi.nlm.nih.gov/pubmed/30310602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01743c
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