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Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives

Heparin (H) and heparan sulfate (HS) belong to the glycosaminoglycan (GAG) family of oligosaccharides, and their sequences and sulfation patterns are known to regulate the functions of various proteins in biological processes. Among these, the 6-O-sulfation of HS/H contributes most significantly to...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Dey, Supriya, Wong, Chi-Huey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115620/
https://ncbi.nlm.nih.gov/pubmed/30310602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01743c
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