Factors influencing pharmacokinetics of warfarin in African–Americans: implications for pharmacogenetic dosing algorithms

AIM: This study attempted to identify predictors of S-warfarin clearance (CL[S]) and to make a pharmacokinetic evaluation of genotype-based dosing algorithms in African–Americans. METHODS: Using plasma S-warfarin concentration (Cp[S]) at a steady state and eight SNPs previously shown to influence wa...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Pharmacogenomics
Huvudupphovsmän: Nagai, Rui, Ohara, Minami, Cavallari, Larisa H, Drozda, Katarzyna, Patel, Shitalben R, Nutescu, Edith A, Perera, Minoli A, Hernandez, Wenndy, Kaneko, Naoko, Hibiya, Manabu, Takahashi, Harumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347085/
https://ncbi.nlm.nih.gov/pubmed/25712185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.160
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk