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Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors

[Image: see text] The development of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is an ongoing and challenging research field. However, the dynamic motion of the binding site of EGFR has not been accurately depicted, hindering the improvement of EGFR TKI. For this reas...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Li, Dong-Dong, Wu, Ting-Ting, Yu, Pan, Wang, Zhen-Zhong, Xiao, Wei, Jiang, Yan, Zhao, Lin-Guo
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346266/
https://ncbi.nlm.nih.gov/pubmed/32656454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02183
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