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Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors

[Image: see text] The development of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is an ongoing and challenging research field. However, the dynamic motion of the binding site of EGFR has not been accurately depicted, hindering the improvement of EGFR TKI. For this reas...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Li, Dong-Dong, Wu, Ting-Ting, Yu, Pan, Wang, Zhen-Zhong, Xiao, Wei, Jiang, Yan, Zhao, Lin-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346266/
https://ncbi.nlm.nih.gov/pubmed/32656454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02183
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