Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases

Duchenne muscular dystrophy (DMD) is caused by mutations in the gene encoding dystrophin. Prior work has shown that DMD progression can vary, depending on the genetic makeup of the patient. Several modifier alleles have been identified including LTBP4 and SPP1. We previously showed that Spp1 exacerb...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Kramerova, Irina, Kumagai-Cresse, Chino, Ermolova, Natalia, Mokhonova, Ekaterina, Marinov, Masha, Capote, Joana, Becerra, Diana, Quattrocelli, Mattia, Crosbie, Rachelle H, Welch, Ellen, McNally, Elizabeth M, Spencer, Melissa J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345878/
https://ncbi.nlm.nih.gov/pubmed/31411676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz181
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados