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The Dystrophin Complex: structure, function and implications for therapy

The dystrophin complex stabilizes the plasma membrane of striated muscle cells. Loss of function mutations in the genes encoding dystrophin, or the associated proteins, triggers instability of the plasma membrane and myofiber loss. Mutations in dystrophin have been extensively cataloged providing re...

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Publicat a:Compr Physiol
Autors principals: Gao, Quan, McNally, Elizabeth M
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767260/
https://ncbi.nlm.nih.gov/pubmed/26140716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphy.c140048
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