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Exon-skipping Therapy for Muscular Dystrophy: A Roadblock, Detour, or Bump in the Road?

Duchenne muscular dystrophy (DMD) affects 1in 5,000 newborn males. These boys appear healthy as infants and young children, but then experience a heartbreaking decline, as muscle tissue gradually wastes away, leaving patients nonambulant by their late teens. The heart and respiratory muscles are sim...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Hoffman, Eric P., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464785/
https://ncbi.nlm.nih.gov/pubmed/24695683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008873
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