Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis

Macrophage activation involves metabolic reprogramming to support antimicrobial cellular functions. How these metabolic shifts influence the outcome of infection by intracellular pathogens remains incompletely understood. Mycobacterium tuberculosis (Mtb) modulates host metabolic pathways and utilize...

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Publicat a:mBio
Autors principals: Chandra, Pallavi, He, Li, Zimmerman, Matthew, Yang, Guozhe, Köster, Stefan, Ouimet, Mireille, Wang, Han, Moore, Kathyrn J., Dartois, Véronique, Schilling, Joel D., Philips, Jennifer A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343992/
https://ncbi.nlm.nih.gov/pubmed/32636249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01139-20
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