Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis

Macrophage activation involves metabolic reprogramming to support antimicrobial cellular functions. How these metabolic shifts influence the outcome of infection by intracellular pathogens remains incompletely understood. Mycobacterium tuberculosis (Mtb) modulates host metabolic pathways and utilize...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Chandra, Pallavi, He, Li, Zimmerman, Matthew, Yang, Guozhe, Köster, Stefan, Ouimet, Mireille, Wang, Han, Moore, Kathyrn J., Dartois, Véronique, Schilling, Joel D., Philips, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343992/
https://ncbi.nlm.nih.gov/pubmed/32636249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01139-20
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