Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA

Mycobacterium tuberculosis’ success as a pathogen comes from its ability to evade degradation by macrophages. Normally macrophages clear microorganisms that activate pathogen-recognition receptors (PRRs) through a lysosomal-trafficking pathway called “LC3-associated phagocytosis” (LAP). Although M....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Köster, Stefan, Upadhyay, Sandeep, Chandra, Pallavi, Papavinasasundaram, Kadamba, Yang, Guozhe, Hassan, Amir, Grigsby, Steven J., Mittal, Ekansh, Park, Heidi S., Jones, Victoria, Hsu, Fong-Fu, Jackson, Mary, Sassetti, Christopher M., Philips, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642705/
https://ncbi.nlm.nih.gov/pubmed/28973896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707792114
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