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Lactate oxidation facilitates growth of Mycobacterium tuberculosis in human macrophages
Mycobacterium tuberculosis (Mtb) uses alveolar macrophages as primary host cells during infection. In response to an infection, macrophages switch from pyruvate oxidation to reduction of pyruvate into lactate. Lactate might present an additional carbon substrate for Mtb. Here, we demonstrate that Mt...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526930/ https://ncbi.nlm.nih.gov/pubmed/28744015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05916-7 |
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