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Agonism of GPR120 prevented IL-1β-induced reduction of extracellular matrix through SOX-9

Osteoarthritis (OA) is a whole-joint disease with extremely high prevalence. In all treatment approaches of OA, blocking the degradation of the cartilage extracellular matrix is an important treatment. In OA, overexpression of derivative enzymes leads to excessive catabolism and reduced synthesis of...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Xu, Zhixian, Ke, Tie, Zhang, Yongfa, Fu, Chaofeng, He, Wubing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343462/
https://ncbi.nlm.nih.gov/pubmed/32580167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103375
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