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Extracellular matrix mechanics regulate transfection and SOX9-directed differentiation of mesenchymal stem cells
Gene delivery within hydrogel matrices can potentially direct mesenchymal stem cells (MSCs) towards a chondrogenic fate to promote regeneration of cartilage. Here, we investigated whether the mechanical properties of the hydrogel containing the gene delivery systems could enhance transfection and ch...
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| Publicado no: | Acta Biomater |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7291356/ https://ncbi.nlm.nih.gov/pubmed/32417266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.04.027 |
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