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Macromolecular Crowding Directs Extracellular Matrix Organization and Mesenchymal Stem Cell Behavior

Microenvironments of biological cells are dominated in vivo by macromolecular crowding and resultant excluded volume effects. This feature is absent in dilute in vitro cell culture. Here, we induced macromolecular crowding in vitro by using synthetic macromolecular globules of nm-scale radius at phy...

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Hlavní autoři: Zeiger, Adam S., Loe, Felicia C., Li, Ran, Raghunath, Michael, Van Vliet, Krystyn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359376/
https://ncbi.nlm.nih.gov/pubmed/22649562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037904
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