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Febuxostat mitigates IL-18-induced inflammatory response and reduction of extracellular matrix gene

Background: Osteoarthritis (OA) is a disease commonly diagnosed in the elderly population. It is reported that the reduction of extracellular matrix and infiltrated inflammation are two main factors responsible for the pathogenesis of OA. This investigation aims to explore the potential protective e...

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Pubblicato in:Am J Transl Res
Autori principali: Geng, Qin, Zhang, Hongju, Cui, Yanhui, Wei, Qiaofeng, Wang, Shujun
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014396/
https://ncbi.nlm.nih.gov/pubmed/33841634
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