Febuxostat mitigates IL-18-induced inflammatory response and reduction of extracellular matrix gene

Background: Osteoarthritis (OA) is a disease commonly diagnosed in the elderly population. It is reported that the reduction of extracellular matrix and infiltrated inflammation are two main factors responsible for the pathogenesis of OA. This investigation aims to explore the potential protective e...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Geng, Qin, Zhang, Hongju, Cui, Yanhui, Wei, Qiaofeng, Wang, Shujun
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2021
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014396/
https://ncbi.nlm.nih.gov/pubmed/33841634
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