Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

Neocortex expansion is largely based on the proliferative capacity of basal progenitors (BPs), which is increased by extracellular matrix (ECM) components via integrin signaling. Here we show that the transcription factor Sox9 drives expression of ECM components and that laminin 211 increases BP pro...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Güven, Ayse, Kalebic, Nereo, Long, Katherine R, Florio, Marta, Vaid, Samir, Brandl, Holger, Stenzel, Denise, Huttner, Wieland B
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2020
Sujets:
Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105383/
https://ncbi.nlm.nih.gov/pubmed/32191207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49808
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires