YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex

Neocortex expansion during mammalian evolution has been linked to an increase in proliferation of basal progenitors in the subventricular zone. Here, we explored a potential role of YAP, the major downstream effector of the Hippo pathway, in proliferation of basal progenitors. YAP expression and act...

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Publicat a:Cell Rep
Autors principals: Kostic, Milos, Paridaen, Judith T.M.L., Long, Katherine R., Kalebic, Nereo, Langen, Barbara, Grübling, Nannette, Wimberger, Pauline, Kawasaki, Hiroshi, Namba, Takashi, Huttner, Wieland B.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486488/
https://ncbi.nlm.nih.gov/pubmed/31018127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.091
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