How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Human type 1 insulin-like growth factor receptor (IGF-1R) signals chiefly in response to the binding of insulin-like growth factor I. Relatively little is known about the role of insulin-like growth factor II signaling via IGF-1R, despite the affinity of insulin-like growth factor II for IGF-1R bein...

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Pubblicato in:Structure
Autori principali: Xu, Yibin, Kirk, Nicholas S., Venugopal, Hariprasad, Margetts, Mai B., Croll, Tristan I., Sandow, Jarrod J., Webb, Andrew I., Delaine, Carlie A., Forbes, Briony E., Lawrence, Michael C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343240/
https://ncbi.nlm.nih.gov/pubmed/32459985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.05.002
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