Herpes Simplex Virus 1 ICP34.5 Alters Mitochondrial Dynamics in Neurons

Expression of viral genes and activation of innate antiviral responses during infection result in an increase in reactive oxygen species (ROS) and toxic by-products of energy metabolism which can lead to cell death. The mitochondrion and its associated proteins are crucial regulators of these respon...

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Bibliographic Details
Published in:J Virol
Main Authors: Manivanh, Richard, Mehrbach, Jesse, Charron, Audra J., Grassetti, Andrew, Cerón, Stacey, Taylor, Sean A., Cabrera, Jorge Rubén, Gerber, Scott, Leib, David A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343198/
https://ncbi.nlm.nih.gov/pubmed/32376626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01784-19
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