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Critical phenomena in the temperature-pressure-crowding phase diagram of a protein

In the cell, proteins fold and perform complex functions through global structural rearrangements. Function requires a protein to be at the brink of stability to be susceptible to small environmental fluctuations, yet stable enough to maintain structural integrity. These apparently conflicting behav...

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Bibliografiske detaljer
Udgivet i:Phys Rev X
Main Authors: Gasic, Andrei G., Boob, Mayank M., Prigozhin, Maxim B., Homouz, Dirar, Wirth, Anna Jean, Daugherty, Caleb M., Gruebele, Martin, Cheung, Margaret S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343146/
https://ncbi.nlm.nih.gov/pubmed/32642303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/physrevx.9.041035
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