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Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNA

Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. The majority of these tumors harbor somatic mutations in genes encoding histone variants. These recurrent mutations correlate with treatment response and are forming t...

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Bibliografische gegevens
Gepubliceerd in:Neurosurg Focus
Hoofdauteurs: Azad, Tej D., Jin, Michael C., Bernhardt, Lydia J., Bettegowda, Chetan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340556/
https://ncbi.nlm.nih.gov/pubmed/31896079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2019.9.FOCUS19699
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