Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

Diffuse midline gliomas (including diffuse intrinsic pontine glioma, DIPG) are highly morbid glial neoplasms of the thalamus or brainstem that typically arise in young children and are not surgically resectable. These tumors are characterized by a high rate of histone H3 mutation, resulting in repla...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Huang, Tina Y., Piunti, Andrea, Lulla, Rishi R., Qi, Jin, Horbinski, Craig M., Tomita, Tadanori, James, C. David, Shilatifard, Ali, Saratsis, Amanda M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392913/
https://ncbi.nlm.nih.gov/pubmed/28416018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0436-6
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