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Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNA

Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. The majority of these tumors harbor somatic mutations in genes encoding histone variants. These recurrent mutations correlate with treatment response and are forming t...

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Bibliografiske detaljer
Udgivet i:Neurosurg Focus
Main Authors: Azad, Tej D., Jin, Michael C., Bernhardt, Lydia J., Bettegowda, Chetan
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340556/
https://ncbi.nlm.nih.gov/pubmed/31896079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2019.9.FOCUS19699
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