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Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNA

Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. The majority of these tumors harbor somatic mutations in genes encoding histone variants. These recurrent mutations correlate with treatment response and are forming t...

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Detalhes bibliográficos
Publicado no:Neurosurg Focus
Main Authors: Azad, Tej D., Jin, Michael C., Bernhardt, Lydia J., Bettegowda, Chetan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340556/
https://ncbi.nlm.nih.gov/pubmed/31896079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2019.9.FOCUS19699
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