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Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNA

Diffuse midline glioma (DMG) is a highly malignant childhood tumor with an exceedingly poor prognosis and limited treatment options. The majority of these tumors harbor somatic mutations in genes encoding histone variants. These recurrent mutations correlate with treatment response and are forming t...

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Bibliografski detalji
Izdano u:Neurosurg Focus
Glavni autori: Azad, Tej D., Jin, Michael C., Bernhardt, Lydia J., Bettegowda, Chetan
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340556/
https://ncbi.nlm.nih.gov/pubmed/31896079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2019.9.FOCUS19699
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