Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation

T cell receptor (TCR) stimulation activates diverse kinase pathways, which include the mitogen-activated protein kinases (MAPKs) ERK and p38, the phosphoinositide 3-kinases (PI3Ks), and the kinase mTOR. Although TCR stimulation activates the p38 pathway through a “classical” MAPK cascade that is med...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Jun, Jesse E., Kulhanek, Kayla R., Chen, Hang, Chakraborty, Arup, Roose, Jeroen P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340343/
https://ncbi.nlm.nih.gov/pubmed/31337738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao0736
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