Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity

Mucosal barrier immunity is essential for the maintenance of the commensal microflora and combating invasive bacterial infection. Although immune and epithelial cells are thought to be the canonical orchestrators of this complex equilibrium, here, we show that the enteric nervous system (ENS) plays...

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Udgivet i:Cell
Main Authors: Jarret, Abigail, Jackson, Ruaidhrí, Duizer, Coco, Healy, Marc E., Zhao, Jun, Rone, Joseph M., Bielecki, Piotr, Sefik, Esen, Roulis, Manolis, Rice, Tyler, Sivanathan, Kisha N., Zhou, Ting, Solis, Angel G., Honcharova-Biletska, Hanna, Vélez, Karelia, Hartner, Saskia, Low, Jun Siong, Qu, Rihao, de Zoete, Marcel R., Palm, Noah W., Ring, Aaron M., Weber, Achim, Moor, Andreas E., Kluger, Yuval, Nowarski, Roni, Flavell, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339937/
https://ncbi.nlm.nih.gov/pubmed/31923399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.016
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