CYP11A1-derived vitamin D(3) products protect against UVB-induced inflammation and promote keratinocytes differentiation

UVB radiation mediates inflammatory responses causing skin damage and defects in epidermal differentiation. 1α,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) interacts with the vitamin D(3) receptor (VDR) to regulate inflammatory responses. Additionally, 1,25(OH)(2)D(3)/VDR signaling represents a potent...

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Publicado no:Free Radic Biol Med
Main Authors: Chaiprasongsuk, Anyamanee, Janjetovic, Zorica, Kim, Tae-Kang, Tuckey, Robert C., Li, Wei, Raman, Chander, Panich, Uraiwan, Slominski, Andrzej T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339935/
https://ncbi.nlm.nih.gov/pubmed/32447000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.05.016
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