Hydroxylumisterols, Photoproducts of Pre-Vitamin D3, Protect Human Keratinocytes against UVB-Induced Damage

Lumisterol (L3) is a stereoisomer of 7-dehydrocholesterol and is produced through the photochemical transformation of 7-dehydrocholesteol induced by high doses of UVB. L3 is enzymatically hydroxylated by CYP11A1, producing 20(OH)L3, 22(OH)L3, 20,22(OH)2L3, and 24(OH)L3. Hydroxylumisterols function a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chaiprasongsuk, Anyamanee, Janjetovic, Zorica, Kim, Tae-Kang, Schwartz, Cynthia J., Tuckey, Robert C., Tang, Edith K. Y., Raman, Chander, Panich, Uraiwan, Slominski, Andrzej T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763359/
https://ncbi.nlm.nih.gov/pubmed/33317048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249374
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