Novel vitamin D photoproducts and their precursors in the skin

Novel metabolic pathways initiated by the enzymatic action of CYP11A1 on 7DHC (7-dehydrocholesterol), ergosterol, vitamins D3 and D2 were characterized with help of chemical synthesis, UV and mass spectrometry and NMR analyses. The first pathway follows the sequence 7DHC→22(OH)7DHC → 20,22(OH)27DHC...

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Bibliographic Details
Main Authors: Slominski, Andrzej, Kim, Tae-Kang, Zmijewski, Michal A., Janjetovic, Zorica, Li, Wei, Chen, Jianjun, Kusniatsova, Ekaterina I., Semak, Igor, Postlethwaite, Arnold, Miller, Duane D., Zjawiony, Jordan K., Tuckey, Robert C.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897599/
https://ncbi.nlm.nih.gov/pubmed/24494038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/derm.23938
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