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Pharmacophore-based virtual screening for the identification of the novel Src inhibitor SJG-136 against lung cancer cell growth and motility

Aberrant elevated Src activity is related to lung cancer growth and metastasis. Therefore, the development of potent small molecule inhibitors to target Src kinase is a potential therapeutic strategy for lung cancer. This study aimed to develop a computational model for the in silico screening of Sr...

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Publicado no:Am J Cancer Res
Main Authors: Weng, Chia-Wei, Li, Jia-Hua, Tsai, Jeng-Yuan, Lin, Shih-Hsuan, Chang, Gee-Chen, Liu, Chun-Chi, Chen, Jeremy JW
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339285/
https://ncbi.nlm.nih.gov/pubmed/32642283
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