Pharmacophore-based virtual screening for the identification of the novel Src inhibitor SJG-136 against lung cancer cell growth and motility

Aberrant elevated Src activity is related to lung cancer growth and metastasis. Therefore, the development of potent small molecule inhibitors to target Src kinase is a potential therapeutic strategy for lung cancer. This study aimed to develop a computational model for the in silico screening of Sr...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Weng, Chia-Wei, Li, Jia-Hua, Tsai, Jeng-Yuan, Lin, Shih-Hsuan, Chang, Gee-Chen, Liu, Chun-Chi, Chen, Jeremy JW
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339285/
https://ncbi.nlm.nih.gov/pubmed/32642283
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