Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

Oncogenic transformation is associated with profound changes in cellular metabolism, but whether tracking these can improve disease stratification or influence therapy decision-making is largely unknown. Using the iKnife to sample the aerosol of cauterized specimens, we demonstrate a new mode of rea...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Koundouros, Nikos, Karali, Evdoxia, Tripp, Aurelien, Valle, Adamo, Inglese, Paolo, Perry, Nicholas J.S., Magee, David J., Anjomani Virmouni, Sara, Elder, George A., Tyson, Adam L., Dória, Maria Luisa, van Weverwijk, Antoinette, Soares, Renata F., Isacke, Clare M., Nicholson, Jeremy K., Glen, Robert C., Takats, Zoltan, Poulogiannis, George
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339148/
https://ncbi.nlm.nih.gov/pubmed/32559461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.053
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