Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

Oncogenic transformation is associated with profound changes in cellular metabolism, but whether tracking these can improve disease stratification or influence therapy decision-making is largely unknown. Using the iKnife to sample the aerosol of cauterized specimens, we demonstrate a new mode of rea...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Koundouros, Nikos, Karali, Evdoxia, Tripp, Aurelien, Valle, Adamo, Inglese, Paolo, Perry, Nicholas J.S., Magee, David J., Anjomani Virmouni, Sara, Elder, George A., Tyson, Adam L., Dória, Maria Luisa, van Weverwijk, Antoinette, Soares, Renata F., Isacke, Clare M., Nicholson, Jeremy K., Glen, Robert C., Takats, Zoltan, Poulogiannis, George
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339148/
https://ncbi.nlm.nih.gov/pubmed/32559461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.053
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