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PARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN

Cancer and Parkinson disease (PD) derive from distinct alterations in cellular processes, yet there are pathogenic mutations that are unequivocally linked to both diseases. Here we expand on our recent findings that loss of parkin RBR E3 ubiquitin protein ligase (PRKN, best known as PARK2)—which is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cell Oncol
मुख्य लेखकों: Gupta, Amit, Anjomani-Virmouni, Sara, Koundouros, Nikos, Poulogiannis, George
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706935/
https://ncbi.nlm.nih.gov/pubmed/29209642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1329692
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