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Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

Metabolic rewiring and the consequent production of reactive oxygen species (ROS) are necessary to promote tumorigenesis. At the nexus of these cellular processes is the aberrant regulation of oncogenic signaling cascades such as the phosphoinositide 3-kinase and AKT (PI3K/Akt) pathway, which is one...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Koundouros, Nikos, Poulogiannis, George
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968394/
https://ncbi.nlm.nih.gov/pubmed/29868481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00160
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