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Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

Metabolic rewiring and the consequent production of reactive oxygen species (ROS) are necessary to promote tumorigenesis. At the nexus of these cellular processes is the aberrant regulation of oncogenic signaling cascades such as the phosphoinositide 3-kinase and AKT (PI3K/Akt) pathway, which is one...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Koundouros, Nikos, Poulogiannis, George
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968394/
https://ncbi.nlm.nih.gov/pubmed/29868481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00160
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