Llwytho...

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

Hedgehogs (Hhs) are key signaling regulators of stem cell maintenance and tissue patterning in embryos, and activating mutations in the pathway that increase Gli transcriptional activity are causal in a diversity of cancers. Here, we report that phosphoinositide 3-kinase (PI3-kinase)-dependent Akt a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Riobó, Natalia A., Lu, Ke, Ai, Xingbin, Haines, Gwendolyn M., Emerson, Charles P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450201/
https://ncbi.nlm.nih.gov/pubmed/16537363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504337103
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