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Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling
Hedgehogs (Hhs) are key signaling regulators of stem cell maintenance and tissue patterning in embryos, and activating mutations in the pathway that increase Gli transcriptional activity are causal in a diversity of cancers. Here, we report that phosphoinositide 3-kinase (PI3-kinase)-dependent Akt a...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2006
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450201/ https://ncbi.nlm.nih.gov/pubmed/16537363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504337103 |
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