Positive Reinforcing Mechanisms Between GPR120 and PPARγ Modulate Insulin Sensitivity

G Protein-coupled receptor 120 (GPR120) and PPARγ agonists each have insulin sensitizing effects. But whether these two pathways functionally interact and can be leveraged together to markedly improve insulin resistance has not been explored. Here, we show that treatment with the PPARγ agonist rosig...

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Publicado en:Cell Metab
Main Authors: Paschoal, Vivian A., Walenta, Evelyn, Talukdar, Saswata, Pessentheiner, Ariane R., Osborn, Olivia, Hah, Nasun, Chi, Tyler J., Tye, George L., Armando, Aaron M., Evans, Ronald M., Chi, Nai-Wen, Quehenberger, Oswald, Olefsky, Jerrold M., Oh, Da Young
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337476/
https://ncbi.nlm.nih.gov/pubmed/32413335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.04.020
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