Positive Reinforcing Mechanisms Between GPR120 and PPARγ Modulate Insulin Sensitivity

G Protein-coupled receptor 120 (GPR120) and PPARγ agonists each have insulin sensitizing effects. But whether these two pathways functionally interact and can be leveraged together to markedly improve insulin resistance has not been explored. Here, we show that treatment with the PPARγ agonist rosig...

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書誌詳細
出版年:Cell Metab
主要な著者: Paschoal, Vivian A., Walenta, Evelyn, Talukdar, Saswata, Pessentheiner, Ariane R., Osborn, Olivia, Hah, Nasun, Chi, Tyler J., Tye, George L., Armando, Aaron M., Evans, Ronald M., Chi, Nai-Wen, Quehenberger, Oswald, Olefsky, Jerrold M., Oh, Da Young
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337476/
https://ncbi.nlm.nih.gov/pubmed/32413335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.04.020
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